Hemodialysis-induced changes in hematocrit, hemoglobin and total protein: Implications for relative blood volume monitoring

Relative blood volume changes underestimate total blood volume changes during hemodialysis.

BACKGROUND Measurements of relative blood volume changes (DeltaRBV) during hemodialysis (HD) are based on hemoconcentration and assume uniform mixing of erythrocytes and plasma throughout the circulation. However, whole-body hematocrit (Ht) is lower than systemic Ht. During HD, a change in the ratio between whole-body to systemic Ht (F cell ratio) is likely to occur as a result of a net shift o...

Do changes in relative blood volume monitoring correlate to hemodialysis-associated hypotension?

INTRODUCTION Intradialytic hypotension remains the most common complication for outpatient hemodialysis, and relative blood volume monitoring was designed to reduce hypotension. Reports of the usefulness of this technology, however, have been variable. METHODS We audited the usefulness of relative blood volume monitoring recorded throughout the mid-week dialysis in 72 stable adult outpatients...

Effects of relative blood volume-controlled hemodialysis on blood pressure and volume status in hypertensive patients.

In hypertensive hemodialysis (HD) patients, dry weight reduction to normalize blood pressure (BP) often results in increased frequency of HD hypotension. Because HD with blood volume tracking (BVT) has been shown to improve intra-HD hemodynamic stability, we performed a prospective, randomized study to test whether BVT is more effective than standard hemodialysis (SHD) in the management of hype...

Hemoglobin concentration, total hemoglobin mass and plasma volume in patients: implications for anemia

In practice, clinicians generally consider anemia (circulating hemoglobin concentration < 120 g.l-1 in non-pregnant females and < 130 g.l-1 in males) as due to impaired hemoglobin synthesis or increased erythrocyte loss or destruction. Rarely is a rise in plasma volume relative to circulating total hemoglobin mass considered as a cause. But does this matter? We explored this issue in patients, ...

Postoperative Changes in Hemoglobin and Hematocrit in Patients Undergoing Primary Total Hip and Knee Arthroplasty